EZM0414 is a selective,potent SETD2 Inhibitor (IC50 = 18 nM) with good pharmacokinetic properties and robust pharmacodynamic activity in a mouse xenograft model.
MedKoo Cat#: 466294
Name: EZM0414
CAS#: 2411748-50-8
Chemical Formula: C24H33FN4O2
Exact Mass: 428.2588
Molecular Weight: 428.55
Elemental Analysis: C, 67.26; H, 7.76; F, 4.43; N, 13.07; O, 7.47
The following data is based on the product molecular weight 428.55 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
