MedKoo Cat#: 471183 | Name: GSK-843
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GSK-843 is a potent ATP-competitive RIP3 (RIPK3) kinase inhibitor.

Chemical Structure

GSK-843
GSK-843
CAS# 1601496-05-2

Theoretical Analysis

MedKoo Cat#: 471183

Name: GSK-843

CAS#: 1601496-05-2

Chemical Formula: C19H15N5S2

Exact Mass: 377.0769

Molecular Weight: 377.48

Elemental Analysis: C, 60.46; H, 4.01; N, 18.55; S, 16.99

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
1g USD 4,450.00 2 Weeks
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Related CAS #
No Data
Synonym
GSK-843, GSK843, GSK 843
IUPAC/Chemical Name
3-(5-Benzothiazolyl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)-thieno[3,2-c]pyridin-4-amine
InChi Key
BPKSNNJTKPIZKR-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H15N5S2/c1-10-5-15(24(2)23-10)12-7-21-19(20)17-13(8-25-18(12)17)11-3-4-16-14(6-11)22-9-26-16/h3-9H,1-2H3,(H2,20,21)
SMILES Code
NC1=NC=C(C2=CC(C)=NN2C)C3=C1C(C4=CC=C(SC=N5)C5=C4)=CS3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 377.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Zhang Y, Wang Y, Zhao W, Li L, Li L, Sun Y, Shao J, Ren X, Zang W, Cao J. Role of spinal RIP3 in inflammatory pain and electroacupuncture-mediated analgesic effect in mice. Life Sci. 2022 Oct 1;306:120839. doi: 10.1016/j.lfs.2022.120839. Epub 2022 Jul 25. PMID: 35902029.