MedKoo Cat#: 112096 | Name: COTC
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

COTC is a bacterial metabolite that has anticancer activity and inhibits glyoxalase in the presence of glutathione (GSH) and the proliferation of HeLa cells, as well as reduces tumor growth and improves survival in an Ehrlich murine spontaneous adenocarcinoma model.

Chemical Structure

COTC
COTC
CAS#57449-30-6

Theoretical Analysis

MedKoo Cat#: 112096

Name: COTC

CAS#: 57449-30-6

Chemical Formula: C11H14O6

Exact Mass: 242.0790

Molecular Weight: 242.23

Elemental Analysis: C, 54.54; H, 5.83; O, 39.63

Price and Availability

Size Price Availability Quantity
1mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
COTC; 2-Crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone
IUPAC/Chemical Name
((3R,4R,5R)-3,4,5-trihydroxy-6-oxocyclohex-1-en-1-yl)methyl (E)-but-2-enoate
InChi Key
PSJQCAMBOYBQEU-KHSNLZPESA-N
InChi Code
InChI=1S/C11H14O6/c1-2-3-8(13)17-5-6-4-7(12)10(15)11(16)9(6)14/h2-4,7,10-12,15-16H,5H2,1H3/b3-2+/t7-,10-,11+/m1/s1
SMILES Code
C/C=C/C(OCC1=C[C@H]([C@H]([C@H](C1=O)O)O)O)=O
Appearance
Solid powder
Purity
>90% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 242.23 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL