MedKoo Cat#: 112057 | Name: Traumatic Acid
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Traumatic acid is a wound healing agent that stimulates cell division near a wound site to form a protective callus.

Chemical Structure

Traumatic Acid
Traumatic Acid
CAS#6402-36-4

Theoretical Analysis

MedKoo Cat#: 112057

Name: Traumatic Acid

CAS#: 6402-36-4

Chemical Formula: C12H20O4

Exact Mass: 228.1362

Molecular Weight: 228.29

Elemental Analysis: C, 63.14; H, 8.83; O, 28.03

Price and Availability

Size Price Availability Quantity
500mg USD 400.00 2 Weeks
1g USD 650.00 2 Weeks
5g USD 1,250.00 2 Weeks
10g USD 1,850.00 2 Weeks
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Related CAS #
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Synonym
Traumatic Acid; trans-2-Dodecenedioic Acid
IUPAC/Chemical Name
(Z)-dodec-2-enedioic acid
InChi Key
MAZWDMBCPDUFDJ-CLFYSBASSA-N
InChi Code
InChI=1S/C12H20O4/c13-11(14)9-7-5-3-1-2-4-6-8-10-12(15)16/h7,9H,1-6,8,10H2,(H,13,14)(H,15,16)/b9-7-
SMILES Code
OC(CCCCCCCC/C=C\C(O)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 228.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Jiang L, Liu P, Wang M, Deng Q, Wang J, Jiang Y, Zhu Y, Meng H, Lu X, Kong X, Chen L. Effect of high-intensity intermittent rehabilitation training on physical function, gut microbiome and metabolite after percutaneous coronary intervention in patients with coronary heart disease. Front Cardiovasc Med. 2024 Nov 28;11:1508456. doi: 10.3389/fcvm.2024.1508456. PMID: 39669411; PMCID: PMC11634878. 2: Xue Y, Lin S, Chen M, Ke J, Zhang J, Fan Q, Chen Y, Chen F. Altered colonic microflora and its metabolic profile in mice with acute viral myocarditis induced by coxsackievirus B3. Virol J. 2024 Nov 16;21(1):295. doi: 10.1186/s12985-024-02571-z. PMID: 39550578; PMCID: PMC11568606. 3: Jiang D, Zhao J, Zheng J, Zhao Y, Le M, Qin D, Huang Q, Huang J, Zhao Q, Wang L, Dong X. LOX-mediated ECM mechanical stress induces Piezo1 activation in hypoxic-ischemic brain damage and identification of novel inhibitor of LOX. Redox Biol. 2024 Oct;76:103346. doi: 10.1016/j.redox.2024.103346. Epub 2024 Sep 7. PMID: 39260063; PMCID: PMC11414707. 4: Zhu Z, Feng YD, Zou YL, Xiao YH, Wu JJ, Yang YR, Jiang XX, Wang L, Xu W. Integrating serum pharmacochemistry, network pharmacology and untargeted metabolomics strategies to reveal the material basis and mechanism of action of Feining keli in the treatment of chronic bronchitis. J Ethnopharmacol. 2024 Dec 5;335:118643. doi: 10.1016/j.jep.2024.118643. Epub 2024 Jul 31. PMID: 39089660. 5: Jin YW, Ma YR, Liu YT, Yang JR, Zhang MK, Ran FL, Chen Y, Wu XA. Identification of a substrate of the renal tubular transporters for detecting drug-induced early acute kidney injury. Toxicol Sci. 2024 Oct 1;201(2):190-205. doi: 10.1093/toxsci/kfae093. PMID: 39041788. 6: Chen KD, Wang KL, Chen C, Zhu YJ, Tang WW, Wang YJ, Chen ZP, He LH, Chen YG, Zhang W. Hydrogen-rich water alleviates constipation by attenuating oxidative stress through the sirtuin1/nuclear factor-erythroid-2-related factor 2/heme oxygenase-1 signaling pathway. World J Gastroenterol. 2024 May 28;30(20):2709-2725. doi: 10.3748/wjg.v30.i20.2709. PMID: 38855154; PMCID: PMC11154682. 7: Jiang S, Zhou Y, Gao J, Jin S, Pan G, Jiang Y. Urinary metabolomic profiles uncover metabolic pathways in children with asthma. J Asthma. 2024 Oct;61(10):1306-1315. doi: 10.1080/02770903.2024.2338865. Epub 2024 Apr 23. PMID: 38634666. 8: Gao J, Zhang Z, Dong X, Zhao J, Peng Z, Zhang L, Xu Z, Xu L, Wang X, Guo X. Traumatic acid inhibits ACSL4 associated lipid accumulation in adipocytes to attenuate high-fat diet-induced obesity. FASEB J. 2023 Dec;37(12):e23278. doi: 10.1096/fj.202301166R. PMID: 37902573. 9: Sowa I, Paduch R, Mołdoch J, Szczepanek D, Szkutnik J, Sowa P, Tyszczuk-Rotko K, Blicharski T, Wójciak M. Antioxidant and Cytotoxic Potential of Carlina vulgaris Extract and Bioactivity-Guided Isolation of Cytotoxic Components. Antioxidants (Basel). 2023 Sep 1;12(9):1704. doi: 10.3390/antiox12091704. PMID: 37760007; PMCID: PMC10525758. 10: Sowa I, Mołdoch J, Paduch R, Strzemski M, Szkutnik J, Tyszczuk-Rotko K, Dresler S, Szczepanek D, Wójciak M. Polyphenolic Composition of Carlina acaulis L. Extract and Cytotoxic Potential against Colorectal Adenocarcinoma and Cervical Cancer Cells. Molecules. 2023 Aug 20;28(16):6148. doi: 10.3390/molecules28166148. PMID: 37630400; PMCID: PMC10458490. 11: Wu ZZ, Gan ZW, Zhang YX, Chen SB, Gan CD, Yang K, Yang JY. Transcriptomic and metabolomic perspectives for the growth of alfalfa (Medicago sativa L.) seedlings with the effect of vanadium exposure. Chemosphere. 2023 Sep;336:139222. doi: 10.1016/j.chemosphere.2023.139222. Epub 2023 Jun 20. PMID: 37343642. 12: Shi X, Shi J, Yu L, Wu X. Metabolic profiling of Apis mellifera larvae treated with sublethal acetamiprid doses. Ecotoxicol Environ Saf. 2023 Apr 1;254:114716. doi: 10.1016/j.ecoenv.2023.114716. Epub 2023 Mar 2. PMID: 36870311. 13: Madkour M, Giddey AD, Soares NC, Semreen MH, Bustanji Y, Zeb F, Halwani R, Faris ME. Ramadan diurnal intermittent fasting is associated with significant plasma metabolomics changes in subjects with overweight and obesity: A prospective cohort study. Front Nutr. 2023 Jan 9;9:1008730. doi: 10.3389/fnut.2022.1008730. PMID: 36698470; PMCID: PMC9868699. 14: Tang M, Zhang H, Wan Y, Deng Z, Qin X, Li R, Liu F. Transcriptome Analysis in Response to Infection of Xanthomonas oryzae pv. oryzicola Strains with Different Pathogenicity. Int J Mol Sci. 2022 Dec 20;24(1):14. doi: 10.3390/ijms24010014. PMID: 36613454; PMCID: PMC9820197. 15: Savchenko T, Degtyaryov E, Radzyukevich Y, Buryak V. Therapeutic Potential of Plant Oxylipins. Int J Mol Sci. 2022 Nov 23;23(23):14627. doi: 10.3390/ijms232314627. PMID: 36498955; PMCID: PMC9741157. 16: Tao Y, Bao J, Zhu F, Pan M, Liu Q, Wang P. Ethnopharmacology of Rubus idaeus Linnaeus: A critical review on ethnobotany, processing methods, phytochemicals, pharmacology and quality control. J Ethnopharmacol. 2023 Feb 10;302(Pt A):115870. doi: 10.1016/j.jep.2022.115870. Epub 2022 Oct 29. PMID: 36341819. 17: Zha X, Li G, Zhang L, Chen Q, Xia Q. Identification of active compounds in Ophiopogonis Radix from different geographical origins by UPLC-Q/TOF-MS combined with GC-MS approaches. Open Life Sci. 2022 Aug 12;17(1):865-880. doi: 10.1515/biol-2022-0096. PMID: 36045721; PMCID: PMC9375982. 18: Xin Y, Yu K, Yu Y, Wang H. Filtration and qualification for target biomarkers of traditional Chinese medicine formula "fuzi lizhong decoction" acting on stomach ulcer by UPLC/Q-TOF MS. Pak J Pharm Sci. 2022 Mar;35(2):519-528. PMID: 35642408. 19: Shen Z, Zheng P, Li R, Sun X, Chen P, Wu D. High production of jasmonic acid by Lasiodiplodia iranensis using solid-state fermentation: Optimization and understanding. Biotechnol J. 2022 May;17(5):e2100550. doi: 10.1002/biot.202100550. Epub 2022 Feb 5. PMID: 35088946. 20: Tsai JS, Wang SY, Chang CH, Chen CY, Wen CJ, Chen GY, Kuo CH, Tseng YJ, Chen CY. Identification of traumatic acid as a potential plasma biomarker for sarcopenia using a metabolomics-based approach. J Cachexia Sarcopenia Muscle. 2022 Feb;13(1):276-286. doi: 10.1002/jcsm.12895. Epub 2021 Dec 22. PMID: 34939349; PMCID: PMC8818620.