Nybomycin succinate | CAS# 5978-64-3 | Antifungal

MedKoo Cat#: 578341 | Name: Nybomycin succinate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Nybomycin succinate is a fungal metabolite with antibacterial activity. It is active against B. subtilis, B. cereus, B. mycoides, M. smegmatis, and K. pneumoniae. Nybomycin is also active against M. tuberculosis and M. bovis.

Chemical Structure

Nybomycin succinate

CAS#5978-64-3

Theoretical Analysis

MedKoo Cat#: 578341

Name: Nybomycin succinate

CAS#: 5978-64-3

Chemical Formula: C20H18N2O7

Exact Mass: 398.1114

Molecular Weight: 398.37

Elemental Analysis: C, 60.30; H, 4.55; N, 7.03; O, 28.11

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Nybomycin succinate

IUPAC/Chemical Name

4-((1-formyl-6,9-dimethyl-2,8-dioxo-1,2,8,9-tetrahydropyrido[3,2-g]quinolin-4-yl)methoxy)-4-oxobutanoic acid

InChi Key

XGSMZMKNFPOBKN-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H18N2O7/c1-11-5-17(24)21(2)15-8-16-14(7-13(11)15)12(6-18(25)22(16)10-23)9-29-20(28)4-3-19(26)27/h5-8,10H,3-4,9H2,1-2H3,(H,26,27)

SMILES Code

CN1C(=O)C=C(C)c2cc3C(=CC(=O)N(C=O)c3cc12)COC(=O)CCC(=O)O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 398.37 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Strelitz, F., Flon, H., and Asheshov, I.N. Nybomycin, a new antibiotic with antiphage and antibacterial properties. Proc. Natl. Acad. Sci. U.S.A. 41(9), 620-624 (1955). 2. Arai, M., Kamiya, K., Pruksakorn, P., et al. Anti-dormant mycobacterial activity and target analysis of nybomycin produced by a marine-derived Streptomyces sp. Bioorg. Med. Chem. 23(13), 3534-3541 (2015).