NZ-107 | CAS# 107186-52-7 | Biochemical

MedKoo Cat#: 578336 | Name: NZ-107

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NZ-107 is an LTB4, LTC4 and LTD4 antagonist.

Chemical Structure

NZ-107

CAS#107186-52-7

Theoretical Analysis

MedKoo Cat#: 578336

Name: NZ-107

CAS#: 107186-52-7

Chemical Formula: C14H16BrN3O3

Exact Mass: 353.0375

Molecular Weight: 354.20

Elemental Analysis: C, 47.47; H, 4.55; Br, 22.56; N, 11.86; O, 13.55

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NZ 107; NZ107; NZ-107

IUPAC/Chemical Name

3(2H)-Pyridazinone, 4-bromo-5-(((3-ethoxy-4-methoxyphenyl)methyl)amino)-

InChi Key

KNIKAZNCSPYOED-UHFFFAOYSA-N

InChi Code

InChI=1S/C14H16BrN3O3/c1-3-21-12-6-9(4-5-11(12)20-2)7-16-10-8-17-18-14(19)13(10)15/h4-6,8H,3,7H2,1-2H3,(H2,16,18,19)

SMILES Code

CCOc1cc(CNC2=C(Br)C(=O)NN=C2)ccc1OC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 354.20 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Nagai H, Suda H, Iwama T, Daikoku M, Yanagihara Y, Koda A. Effect of NZ-107, a newly synthesized pyridazinone derivative, on antigen-induced contraction of human bronchial strips and histamine release from human lung fragments or leukocytes. Int Arch Allergy Immunol. 1992;98(1):57-63. doi: 10.1159/000236164. PMID: 1378042. 2. Suda H, Nagai H, Miura T, Iwama T, Koda A. Effects of a newly synthesized leukotriene antagonist, NZ-107, on immediate-type hypersensitivity reaction in rats and guinea-pigs. Prostaglandins Leukot Essent Fatty Acids. 1992 Sep;47(1):41-9. doi: 10.1016/0952-3278(92)90184-k. PMID: 1279732.