NPS-467 | CAS# 148717-47-9 | Biochemical

MedKoo Cat#: 578322 | Name: NPS-467

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NPS-467 is a specific CaR agonist.

Chemical Structure

NPS-467

CAS#148717-47-9

Theoretical Analysis

MedKoo Cat#: 578322

Name: NPS-467

CAS#: 148717-47-9

Chemical Formula: C18H23NO

Exact Mass: 269.1780

Molecular Weight: 269.39

Elemental Analysis: C, 80.26; H, 8.61; N, 5.20; O, 5.94

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NPS-467; NPS 467; NPS467

IUPAC/Chemical Name

Benzenepropanamine, N-(1-(3-methoxyphenyl)ethyl)-

InChi Key

WOPAHKKTEVUGOE-UHFFFAOYSA-N

InChi Code

InChI=1S/C18H23NO/c1-15(17-11-6-12-18(14-17)20-2)19-13-7-10-16-8-4-3-5-9-16/h3-6,8-9,11-12,14-15,19H,7,10,13H2,1-2H3

SMILES Code

COc1cccc(c1)C(C)NCCCc2ccccc2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 269.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Hammerland LG, Garrett JE, Hung BC, Levinthal C, Nemeth EF. Allosteric activation of the Ca2+ receptor expressed in Xenopus laevis oocytes by NPS 467 or NPS 568. Mol Pharmacol. 1998 Jun;53(6):1083-8. PMID: 9614212. 2. Bandyopadhyay S, Jeong KH, Hansen JT, Vassilev PM, Brown EM, Chattopadhyay N. Calcium-sensing receptor stimulates secretion of an interferon-gamma-induced monokine (CXCL10) and monocyte chemoattractant protein-3 in immortalized GnRH neurons. J Neurosci Res. 2007 Mar;85(4):882-95. doi: 10.1002/jnr.21177. PMID: 17285630.