MedKoo Cat#: 578261 | Name: KNI-144

Description:

WARNING: This product is for research use only, not for human or veterinary use.

KNI-144 is a protease inhibitor.

Chemical Structure

KNI-144
KNI-144
CAS#141171-77-9

Theoretical Analysis

MedKoo Cat#: 578261

Name: KNI-144

CAS#: 141171-77-9

Chemical Formula: C35H43N5O7

Exact Mass: 645.3162

Molecular Weight: 645.76

Elemental Analysis: C, 65.10; H, 6.71; N, 10.85; O, 17.34

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
KNI 144; KNI144; KNI-144
IUPAC/Chemical Name
(S)-N1-((2S,3S)-4-((S)-2-(tert-butylcarbamoyl)pyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)-2-(2-(naphthalen-1-yloxy)acetamido)succinamide
InChi Key
HTMNHRZEFBOZIL-QEETYVBOSA-N
InChi Code
InChI=1S/C35H43N5O7/c1-35(2,3)39-33(45)27-16-10-18-40(27)34(46)31(43)25(19-22-11-5-4-6-12-22)38-32(44)26(20-29(36)41)37-30(42)21-47-28-17-9-14-23-13-7-8-15-24(23)28/h4-9,11-15,17,25-27,31,43H,10,16,18-21H2,1-3H3,(H2,36,41)(H,37,42)(H,38,44)(H,39,45)/t25-,26-,27-,31-/m0/s1
SMILES Code
CC(C)(C)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](O)[C@H](Cc2ccccc2)NC(=O)[C@H](CC(=O)N)NC(=O)COc3cccc4ccccc34
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 645.76 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Sato A, Kodama M, Abe K, Miki S, Nishimura M, Suyama A, Ogata M, Toyoda T, Sugimoto H, Yoshie O, et al. A simple and rapid method for preliminary evaluation of in vivo efficacy of anti-HIV compounds in mice. Antiviral Res. 1995 May;27(1-2):151-63. doi: 10.1016/0166-3542(95)00004-6. PMID: 7486952.