NNL-2 | CAS# 2205044-69-3 | Biochemical

MedKoo Cat#: 578259 | Name: NNL-2

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NNL-2 is a synthetic cannabinoid and T-type calcium channel inhibitor. This product is for research use only.

Chemical Structure

NNL-2

CAS#2205044-69-3

Theoretical Analysis

MedKoo Cat#: 578259

Name: NNL-2

CAS#: 2205044-69-3

Chemical Formula: C25H30FN3O

Exact Mass: 407.2373

Molecular Weight: 407.53

Elemental Analysis: C, 73.68; H, 7.42; F, 4.66; N, 10.31; O, 3.93

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NNL-2; NNL 2; NNL2

IUPAC/Chemical Name

Methanone, (1-(5-fluoropentyl)-1H-indol-3-yl)(4-(phenylmethyl)-1-piperazinyl)-

InChi Key

WHHDMGMJHFYVEK-UHFFFAOYSA-N

InChi Code

1S/C25H30FN3O/c26-13-7-2-8-14-29-20-23(22-11-5-6-12-24(22)29)25(30)28-17-15-27(16-18-28)19-21-9-3-1-4-10-21/h1,3-6,9-12,20H,2,7-8,13-19H2

SMILES Code

FCCCCCn1cc(C(=O)N2CCN(Cc3ccccc3)CC2)c4ccccc14

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 407.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Qian Z, Jia W, Li T, Hua Z, Liu C. Identification and analytical characterization of four synthetic cannabinoids ADB-BICA, NNL-1, NNL-2, and PPA(N)-2201. Drug Test Anal. 2017 Jan;9(1):51-60. doi: 10.1002/dta.1990. Epub 2016 May 30. PMID: 27239006. 2. Kevin RC, Mirlohi S, Manning JJ, Boyd R, Cairns EA, Ametovski A, Lai F, Luo JL, Jorgensen W, Ellison R, Gerona RR, Hibbs DE, McGregor IS, Glass M, Connor M, Bladen C, Zamponi GW, Banister SD. Putative Synthetic Cannabinoids MEPIRAPIM, 5F-BEPIRAPIM (NNL-2), and Their Analogues Are T-Type Calcium Channel (CaV3) Inhibitors. ACS Chem Neurosci. 2022 May 4;13(9):1395-1409. doi: 10.1021/acschemneuro.1c00822. Epub 2022 Apr 20. PMID: 35442021.