NCQ-436 | CAS# 148460-80-4 | Biochemical

MedKoo Cat#: 578027 | Name: NCQ-436

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NCQ-436 is a metabolite of remoxipride.

Chemical Structure

NCQ-436

CAS#148460-80-4

Theoretical Analysis

MedKoo Cat#: 578027

Name: NCQ-436

CAS#: 148460-80-4

Chemical Formula: C15H21BrN2O4

Exact Mass: 372.0685

Molecular Weight: 373.25

Elemental Analysis: C, 48.27; H, 5.67; Br, 21.41; N, 7.51; O, 17.15

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NCQ-436; NCQ 436; NCQ436

IUPAC/Chemical Name

Benzamide, 3-bromo-N-((1-ethyl-2-pyrrolidinyl)methyl)-5,6-dihydroxy-2-methoxy-, (S)-

InChi Key

RJMFJSBUCRXRGR-VIFPVBQESA-N

InChi Code

InChI=1S/C15H21BrN2O4/c1-3-18-6-4-5-9(18)8-17-15(21)12-13(20)11(19)7-10(16)14(12)22-2/h7,9,19-20H,3-6,8H2,1-2H3,(H,17,21)/t9-/m0/s1

SMILES Code

CCN1CCC[C@H]1CNC(=O)c2c(O)c(O)cc(Br)c2OC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 373.25 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Erve JC, Svensson MA, von Euler-Chelpin H, Klasson-Wehler E. Characterization of glutathione conjugates of the remoxipride hydroquinone metabolite NCQ-344 formed in vitro and detection following oxidation by human neutrophils. Chem Res Toxicol. 2004 Apr;17(4):564-71. doi: 10.1021/tx034238n. PMID: 15089099. 2. Ogren SO, Lundström J, Nilsson LB, Widman M. Dopamine D2 blocking activity and plasma concentrations of remoxipride and its main metabolites in the rat. J Neural Transm Gen Sect. 1993;93(3):187-203. doi: 10.1007/BF01244996. PMID: 8217058.