MedKoo Cat#: 578026 | Name: NCQ-298

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NCQ-298 is a selective iodinated salicylamide ligand for the labelling of dopamine D2 receptors.

Chemical Structure

NCQ-298
NCQ-298
CAS#131062-31-2

Theoretical Analysis

MedKoo Cat#: 578026

Name: NCQ-298

CAS#: 131062-31-2

Chemical Formula: C16H23IN2O4

Exact Mass: 434.0703

Molecular Weight: 434.27

Elemental Analysis: C, 44.25; H, 5.34; I, 29.22; N, 6.45; O, 14.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
NCQ 298; NCQ298; NCQ-298
IUPAC/Chemical Name
3-Iodo-N-((1-ethyl-2-pyrrolidinyl)methyl)-5,6-dimethoxysalicylamide
InChi Key
BKJGKGPGPACEQW-JTQLQIEISA-N
InChi Code
InChI=1S/C16H23IN2O4/c1-4-19-7-5-6-10(19)9-18-16(21)13-14(20)11(17)8-12(22-2)15(13)23-3/h8,10,20H,4-7,9H2,1-3H3,(H,18,21)/t10-/m0/s1
SMILES Code
CCN1CCC[C@H]1CNC(=O)c2c(O)c(I)cc(OC)c2OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 434.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Hall H, Högberg T, Halldin C, Köhler C, Ström P, Ross SB, Larsson SA, Farde L. NCQ 298, a new selective iodinated salicylamide ligand for the labelling of dopamine D2 receptors. Psychopharmacology (Berl). 1991;103(1):6-18. doi: 10.1007/BF02244067. PMID: 1672460. 2. Jerning E, Malmberg A, Mohell N. In vitro receptor binding characteristics of the new dopamine D2 antagonist [125I]NCQ-298: methodological considerations of high affinity binding. J Recept Signal Transduct Res. 1995 Jan-Mar;15(1-4):503-15. doi: 10.3109/10799899509045236. PMID: 8903960.