MedKoo Cat#: 471157 | Name: S6K-18
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

S6K-18 is a selective inhibitor of ribosomal protein S6 kinase beta-1.

Chemical Structure

S6K-18
S6K-18
CAS#1265789-88-5

Theoretical Analysis

MedKoo Cat#: 471157

Name: S6K-18

CAS#: 1265789-88-5

Chemical Formula: C17H18N4O3S

Exact Mass: 358.1100

Molecular Weight: 358.42

Elemental Analysis: C, 56.97; H, 5.06; N, 15.63; O, 13.39; S, 8.94

Price and Availability

Size Price Availability Quantity
50mg USD 450.00 2 Weeks
100mg USD 750.00 2 Weeks
200mg USD 1,250.00 2 Weeks
500mg USD 2,850.00 2 Weeks
1g USD 4,250.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
S6K-18; S6K18; S6K 18; S6K1-IN-1; S6K1 IN-1; S6K1-IN 1
IUPAC/Chemical Name
2-(3-(1H-indazol-5-yl)ureido)-5-(tert-butyl)thiophene-3-carboxylic acid
InChi Key
BSRFCMMJUFQEOX-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H18N4O3S/c1-17(2,3)13-7-11(15(22)23)14(25-13)20-16(24)19-10-4-5-12-9(6-10)8-18-21-12/h4-8H,1-3H3,(H,18,21)(H,22,23)(H2,19,20,24)
SMILES Code
O=C(C1=C(NC(NC2=CC3=C(NN=C3)C=C2)=O)SC(C(C)(C)C)=C1)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 358.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Potter, C. J., Pedraza, L. G., & Xu, T. (2002). Akt regulates growth by directly phosphorylating Tsc2. Nature cell biology, 4(9), 658-665. 2. Ye P, Kuhn C, Juan M, Sharma R, Connolly B, Alton G, Liu H, Stanton R, Kablaoui NM. Potent and selective thiophene urea-templated inhibitors of S6K. Bioorg Med Chem Lett. 2011 Jan 15;21(2):849-52. doi: 10.1016/j.bmcl.2010.11.069. Epub 2010 Nov 21. PMID: 21185721.