N-2733 HCl | CAS# 220379-48-6 | Biochemical

MedKoo Cat#: 577918 | Name: N-2733 HCl

Description:

WARNING: This product is for research use only, not for human or veterinary use.

N-2733 HCl is a nuclear factor (NF)-kappaB activation inhibitor.

Chemical Structure

N-2733 HCl

CAS#220379-48-6

Theoretical Analysis

MedKoo Cat#: 577918

Name: N-2733 HCl

CAS#: 220379-48-6

Chemical Formula: C12H13ClN2O2

Exact Mass: 252.0666

Molecular Weight: 252.70

Elemental Analysis: C, 57.04; H, 5.19; Cl, 14.03; N, 11.09; O, 12.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

N 2733 HCl; N2733 HCl; N-2733 HCl; N2733 hydrochloride

IUPAC/Chemical Name

2-Pyrrolidinone, 1-(1-oxo-3-(3-pyridinyl)-2-propen-1-yl)-, hydrochloride (1:1)

InChi Key

JYPXPKYXTLVVIW-IPZCTEOASA-N

InChi Code

1S/C12H12N2O2.ClH/c15-11-4-2-8-14(11)12(16)6-5-10-3-1-7-13-9-10;/h1,3,5-7,9H,2,4,8H2;1H/b6-5+;

SMILES Code

Cl.O=C(\C=C\c1cccnc1)N2CCCC2=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 252.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Mitaka C, Hirata Y, Narumi Y, Yokoyama K, Makita K, Katsuyama K, Imai T. Blockade of nuclear factor-kappaB activation prevents hypodynamic shock and gastric hypoperfusion induced by endotoxin in anesthetized dogs. Intensive Care Med. 2005 May;31(5):718-23. doi: 10.1007/s00134-005-2617-1. Epub 2005 Apr 6. PMID: 15812625.