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MedKoo Cat#: 471146 | Name: Primin
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Primin is a benzoquinone that has diverse biological activities.

Chemical Structure

Primin
CAS#15121-94-5

Theoretical Analysis

MedKoo Cat#: 471146

Name: Primin

CAS#: 15121-94-5

Chemical Formula: C12H16O3

Exact Mass: 208.1100

Molecular Weight: 208.26

Elemental Analysis: C, 69.21; H, 7.74; O, 23.05

Price and Availability

Size Price Availability Quantity
5mg USD 380.00 2 Weeks
10g USD 675.00 2 Weeks
25mg USD 1,000.00 2 Weeks
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Related CAS #
No Data
Synonym
Primin
IUPAC/Chemical Name
2-methoxy-6-pentyl-2,5-cyclohexadiene-1,4-dione
InChi Key
WLWIMKWZMGJRBS-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H16O3/c1-3-4-5-6-9-7-10(13)8-11(15-2)12(9)14/h7-8H,3-6H2,1-2H3
SMILES Code
O=C1C(OC)=CC(C=C1CCCCC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 208.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kiani Dehkian Z, Taheri H, Pakdaman Sardrood B, Farkhari M. Controlling Tomato Fusarium Wilt Disease through Bacillus thuringiensis-Mediated Defense Primining. Iran J Biotechnol. 2024 Jan 1;22(1):e3690. doi: 10.30498/ijb.2024.394291.3690. PMID: 38827338; PMCID: PMC11139446. 2: Hassan S, Mohammed TO, Malik S, Abouchaleh N, Elston DM. Botanical Briefs: Primula obconica Dermatitis. Cutis. 2023 Mar;111(3):138-139. doi: 10.12788/cutis.0721. PMID: 37224501. 3: Todor IN, Lukianova NY, Primin MA, Nedayvoda IV, Chekhun VF. BIOMAGNETISM OF DRUG-SENSITIVE AND DRUG-RESISTANT MALIGNANT TUMORS AFTER INJECTION OF FERROMAGNETIC NANOCOMPOSITE. Exp Oncol. 2022 Dec;44(4):320-323. doi: 10.32471/exp-oncology.2312-8852.vol-44-no-4.19093. PMID: 36811536. 4: Alavi M, Ashengroph M. Mycosynthesis of AgNPs: mechanisms of nanoparticle formation and antimicrobial activities. Expert Rev Anti Infect Ther. 2023 Apr;21(4):355-363. doi: 10.1080/14787210.2023.2179988. Epub 2023 Feb 20. PMID: 36786717. 5: Todor IN, Lukianova NY *, Primin MА, Nedayvoda IV, Chekhun VF. Biomagnetism of tumor in rats with Guerin's carcinoma after injection of ferromagnetic nanocomposite (Ferroplat): contactless measurement. Exp Oncol. 2020 Sep;42(3):204-207. doi: 10.32471/exp-oncology.2312-8852.vol-42-no-3.14918. PMID: 32996742. 6: Sisa M, Dvorakova M, Temml V, Jarosova V, Vanek T, Landa P. Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core. Eur J Med Chem. 2020 Oct 15;204:112620. doi: 10.1016/j.ejmech.2020.112620. Epub 2020 Jul 11. PMID: 32738413. 7: Bigolin A, Maioral MF, Stefanes NM, Zatelli GA, Philippus AC, Falkenberg MB, Santos-Silva MC. Cytotoxic mechanisms of primin, a natural quinone isolated from Eugenia hiemalis, on hematological cancer cell lines. Anticancer Drugs. 2020 Aug;31(7):709-717. doi: 10.1097/CAD.0000000000000937. PMID: 32639281. 8: Boyvat A, Kalay Yildizhan I. Patch test results of the European baseline series among 1309 patients in Turkey between 2013 and 2019. Contact Dermatitis. 2021 Jan;84(1):15-23. doi: 10.1111/cod.13653. Epub 2020 Aug 3. PMID: 32618364. 9: Barnstorf I, Welten SPM, Borsa M, Baumann NS, Pallmer K, Joller N, Spörri R, Oxenius A. Chronic viral infections impinge on naive bystander CD8 T cells. Immun Inflamm Dis. 2020 Sep;8(3):249-257. doi: 10.1002/iid3.300. Epub 2020 Mar 26. PMID: 32220007; PMCID: PMC7416038. 10: Viegas FPD, Espuri PF, Oliver JC, Silva NC, Dias ALT, Marques MJ, Soares MG. Leishmanicidal and antimicrobial activity of primin and primin-containing extracts from Miconia willdenowii. Fitoterapia. 2019 Oct;138:104297. doi: 10.1016/j.fitote.2019.104297. Epub 2019 Aug 9. PMID: 31404617. 11: Teo Y, McFadden JP, White IR, Lynch M, Banerjee P. Allergic contact dermatitis in atopic individuals: Results of a 30-year retrospective study. Contact Dermatitis. 2019 Dec;81(6):409-416. doi: 10.1111/cod.13363. Epub 2019 Aug 16. PMID: 31347185. 12: Wilkinson M, Gallo R, Goossens A, Johansen JD, Rustemeyer T, Sánchez-Pérez J, Schuttelaar ML, Uter W. A proposal to create an extension to the European baseline series. Contact Dermatitis. 2018 Feb;78(2):101-108. doi: 10.1111/cod.12918. Epub 2017 Dec 1. PMID: 29194657. 13: Elser D, Gilli C, Brecker L, Valant-Vetschera KM. Striking Diversification of Exudate Profiles in Selected Primula Lineages. Nat Prod Commun. 2016 May;11(5):585-90. PMID: 27319123. 14: Hervella-Garcés M, García-Gavín J, Silvestre-Salvador JF; en representación del Grupo Español de Investigación en Dermatitis de Contacto y Alergia Cutánea (GEIDAC). The Spanish standard patch test series: 2016 update by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC). Actas Dermosifiliogr. 2016 Sep;107(7):559-66. English, Spanish. doi: 10.1016/j.ad.2016.04.009. Epub 2016 Jun 1. PMID: 27262363. 15: Bongiorni L, Prodi A, Rui F, Belloni Fortina A, Corradin MT, Larese Filon F. Primin sensitization in north-eastern Italy: a temporal trend from 1996 to 2012. Contact Dermatitis. 2015 Aug;73(2):108-12. doi: 10.1111/cod.12385. Epub 2015 Mar 20. PMID: 25799880. 16: Sashida Y. [Dermatitis caused by primulas]. Chudoku Kenkyu. 2014 Mar;27(1):28-30. Japanese. PMID: 24724357. 17: Schoeffler A, Waton J, Latarche C, Poreaux C, Cuny JF, Schmutz JL, Barbaud A. Évolution de la batterie standard européenne de 1981 à 2011 dans un centre de dermato-allergologie français [Changes in the European baseline series from 1981 to 2011 in a French dermatology-allergology centre]. Ann Dermatol Venereol. 2013 Aug-Sep;140(8-9):499-509. French. doi: 10.1016/j.annder.2013.02.012. Epub 2013 Apr 6. PMID: 24034634. 18: Landa P, Kutil Z, Temml V, Malik J, Kokoska L, Widowitz U, Pribylova M, Dvorakova M, Marsik P, Schuster D, Bauer R, Vanek T. Inhibition of in vitro leukotriene B4 biosynthesis in human neutrophil granulocytes and docking studies of natural quinones. Nat Prod Commun. 2013 Jan;8(1):105-8. PMID: 23472470. 19: Uter W, Aberer W, Armario-Hita JC, Fernandez-Vozmediano JM, Ayala F, Balato A, Bauer A, Ballmer-Weber B, Beliauskiene A, Fortina AB, Bircher A, Brasch J, Chowdhury MM, Coenraads PJ, Schuttelaar ML, Cooper S, Czarnecka-Operacz M, Zmudzinska M, Elsner P, English JS, Frosch PJ, Fuchs T, García-Gavín J, Fernández-Redondo V, Gawkrodger DJ, Giménez-Arnau A, Green CM, Horne HL, Johansen JD, Jolanki R, Pesonen M, King CM, Krêcisz B, Chomiczewska D, Kiec- Swierczynska M, Larese F, Mahler V, Ormerod AD, Peserico A, Rantanen T, Rustemeyer T, Sánchez-Pérez J, Sansom JE, Silvestre JF, Simon D, Spiewak R, Statham BN, Stone N, Wilkinson M, Schnuch A. Current patch test results with the European baseline series and extensions to it from the 'European Surveillance System on Contact Allergy' network, 2007-2008. Contact Dermatitis. 2012 Jul;67(1):9-19. doi: 10.1111/j.1600-0536.2012.02070.x. Epub 2012 Apr 15. PMID: 22500724. 20: Landa P, Kutil Z, Temml V, Vuorinen A, Malik J, Dvorakova M, Marsik P, Kokoska L, Pribylova M, Schuster D, Vanek T. Redox and non-redox mechanism of in vitro cyclooxygenase inhibition by natural quinones. Planta Med. 2012 Mar;78(4):326-33. doi: 10.1055/s-0031-1280430. Epub 2011 Dec 15. PMID: 22174077.