MedKoo Cat#: 466127 | Name: CTR-21

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CTR-21, also known as NSC795903, is a novel anticancer agent, effectively killing multi-drug resistant cancer cells and a panel of different cancer cells originated from a variety of different tissues including breast and skin, preventing tubulin polymerization, leading to the cell cycle arrest at G2/M.

Chemical Structure

CTR-21
CTR-21
CAS#2098310-96-2

Theoretical Analysis

MedKoo Cat#: 466127

Name: CTR-21

CAS#: 2098310-96-2

Chemical Formula: C20H17NO4

Exact Mass: 335.1158

Molecular Weight: 335.36

Elemental Analysis: C, 71.63; H, 5.11; N, 4.18; O, 19.08

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CTR-21; CTR21; CTR 21; NSC795903; NSC 795903; NSC-795903;
IUPAC/Chemical Name
(E)-8-methoxy-3-(3-(2-methoxyphenyl)-3-oxoprop-1-en-1-yl)quinolin-2(1H)-one
InChi Key
KMTXOHJJHMCMLQ-ZHACJKMWSA-N
InChi Code
InChI=1S/C20H17NO4/c1-24-17-8-4-3-7-15(17)16(22)11-10-14-12-13-6-5-9-18(25-2)19(13)21-20(14)23/h3-12H,1-2H3,(H,21,23)/b11-10+
SMILES Code
O=C1NC2=C(C=CC=C2OC)C=C1/C=C/C(C3=CC=CC=C3OC)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 335.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Knockleby J, Djigo AD, Lindamulage IK, Karthikeyan C, Trivedi P, Lee H. Lead optimization of novel quinolone chalcone compounds by a structure-activity relationship (SAR) study to increase efficacy and metabolic stability. Sci Rep. 2021 Nov 3;11(1):21576. doi: 10.1038/s41598-021-01058-z. PMID: 34732782; PMCID: PMC8566451.