MedKoo Cat#: 577895 | Name: Tromantadine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tromantadine is an antiviral agent that has been shown to inhibit HSV-1 replication.

Chemical Structure

Tromantadine
Tromantadine
CAS#53783-83-8

Theoretical Analysis

MedKoo Cat#: 577895

Name: Tromantadine

CAS#: 53783-83-8

Chemical Formula: C16H28N2O2

Exact Mass: 280.2151

Molecular Weight: 280.41

Elemental Analysis: C, 68.53; H, 10.07; N, 9.99; O, 11.41

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Tromantadine
IUPAC/Chemical Name
2-(2-(Dimethylamino)ethoxy)-N-tricyclo(3.3.1.1(3,7))dec-1-ylacetamide
InChi Key
UXQDWARBDDDTKG-UHFFFAOYSA-N
InChi Code
InChI=1S/C16H28N2O2/c1-18(2)3-4-20-11-15(19)17-16-8-12-5-13(9-16)7-14(6-12)10-16/h12-14H,3-11H2,1-2H3,(H,17,19)
SMILES Code
CN(C)CCOCC(=O)NC12CC3CC(CC(C3)C1)C2
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 280.41 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Rosenthal KS, Sokol MS, Ingram RL, Subramanian R, Fort RC. Tromantadine: inhibitor of early and late events in herpes simplex virus replication. Antimicrob Agents Chemother. 1982 Dec;22(6):1031-6. doi: 10.1128/AAC.22.6.1031. PMID: 6297383; PMCID: PMC185716. 2. Ickes DE, Venetta TM, Phonphok Y, Rosenthal KS. Tromantadine inhibits a late step in herpes simplex virus type 1 replication and syncytium formation. Antiviral Res. 1990 Aug;14(2):75-85. doi: 10.1016/0166-3542(90)90045-9. PMID: 2177318.