ZD 7155 hydrochloride is a selective and potent antagonist of the angiotensin II type 1 (AT₁) receptor, which regulates blood pressure and vascular resistance. It exhibits high binding affinity, with an IC₅₀ of 3.8 nM, and demonstrates greater potency and longer duration of action than losartan. This compound has been widely used in preclinical research on hypertension and cardiovascular diseases.
MedKoo Cat#: 471138
Name: ZD 7155 hydrochloride
CAS#: 146709-78-6
Chemical Formula: C26H27ClN6O
Exact Mass: 0.0000
Molecular Weight: 474.99
Elemental Analysis: C, 65.75; H, 5.73; Cl, 7.46; N, 17.69; O, 3.37
The following data is based on the product molecular weight 474.99 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
