Synonym
HAM-1; HAM1; HAM 1;
IUPAC/Chemical Name
6-amino-3-(4-fluorophenyl)-4-(3-(4-fluorophenyl)-1H-pyrazol-4-yl)-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile
InChi Key
GKUJGEJKDIGMCJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H14F2N6O/c23-13-5-1-11(2-6-13)19-16(10-27-28-19)17-15(9-25)21(26)31-22-18(17)20(29-30-22)12-3-7-14(24)8-4-12/h1-8,10,17H,26H2,(H,27,28)(H,29,30)
SMILES Code
NC1=C(C#N)C(C2=CNN=C2C3=CC=C(F)C=C3)C(C(C4=CC=C(F)C=C4)=NN5)=C5O1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
416.39
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Fan Y, Yan J, Lai D, Yang H, Xue G, He A, Guo T, Chen L, Cheng XB, Xiang DB, Ruan J, Cheng J. Genome-wide identification, expression analysis, and functional study of the GRAS transcription factor family and its response to abiotic stress in sorghum [Sorghum bicolor (L.) Moench]. BMC Genomics. 2021 Jul 6;22(1):509. doi: 10.1186/s12864-021-07848-z. PMID: 34229611; PMCID: PMC8259154.
2: Wang Y, Hardin H, Chu YH, Esbona K, Zhang R, Lloyd RV. Long Non-coding RNA Expression in Anaplastic Thyroid Carcinomas. Endocr Pathol. 2019 Dec;30(4):262-269. doi: 10.1007/s12022-019-09589-y. PMID: 31468286.
3: Offenburger SL, Bensaddek D, Murillo AB, Lamond AI, Gartner A. Comparative genetic, proteomic and phosphoproteomic analysis of C. elegans embryos with a focus on ham-1/STOX and pig-1/MELK in dopaminergic neuron development. Sci Rep. 2017 Jun 28;7(1):4314. doi: 10.1038/s41598-017-04375-4. PMID: 28659600; PMCID: PMC5489525.
