BZX2 | CAS#1349070-58-1 | OGT activity inhibitor

MedKoo Cat#: 466072 | Name: BZX2

Description:

WARNING: This product is for research use only, not for human or veterinary use.

BZX2 is a novel inhibitor of O-GlcNAc transferase (OGT) activity.

Chemical Structure

BZX2

CAS#1349070-58-1

Theoretical Analysis

MedKoo Cat#: 466072

Name: BZX2

CAS#: 1349070-58-1

Chemical Formula: C17H13NO6

Exact Mass: 327.0743

Molecular Weight: 327.29

Elemental Analysis: C, 62.39; H, 4.00; N, 4.28; O, 29.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

BZX2; BZX-2; BZX 2;

IUPAC/Chemical Name

4-methoxyphenyl 6-acetyl-2-oxobenzo[d]oxazole-3(2H)-carboxylate

InChi Key

OTFIYJFEIKDOGO-UHFFFAOYSA-N

InChi Code

InChI=1S/C17H13NO6/c1-10(19)11-3-8-14-15(9-11)24-17(21)18(14)16(20)23-13-6-4-12(22-2)5-7-13/h3-9H,1-2H3

SMILES Code

O=C(N1C(OC2=CC(C(C)=O)=CC=C12)=O)OC3=CC=C(OC)C=C3

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 327.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lim S, Haque MM, Nam G, Ryoo N, Rhim H, Kim YK. Monitoring of Intracellular Tau Aggregation Regulated by OGA/OGT Inhibitors. Int J Mol Sci. 2015 Aug 26;16(9):20212-24. doi: 10.3390/ijms160920212. PMID: 26343633; PMCID: PMC4613198.