MedKoo Cat#: 577842 | Name: MZ-3

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MZ-3 is a biochemical that has been shown to induce G2/M-phase arrest, inhibit microtubule assemby, and induce apoptosis in human leukemia cells.

Chemical Structure

MZ-3
MZ-3
CAS#848690-52-8

Theoretical Analysis

MedKoo Cat#: 577842

Name: MZ-3

CAS#: 848690-52-8

Chemical Formula: C28H28BrN3O8

Exact Mass: 613.1060

Molecular Weight: 614.45

Elemental Analysis: C, 54.73; H, 4.59; Br, 13.00; N, 6.84; O, 20.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MZ-3; MZ 3; MZ3
IUPAC/Chemical Name
4-(4-Bromophenyl)-2,3-dihydro-2-oxo-N,3-bis(3,4,5-trimethoxyphenyl)-1H-imidazole-1-carboxamide
InChi Key
BOSPIJGSGYQWQR-UHFFFAOYSA-N
InChi Code
1S/C28H28BrN3O8/c1-35-21-11-18(12-22(36-2)25(21)39-5)30-27(33)31-15-20(16-7-9-17(29)10-8-16)32(28(31)34)19-13-23(37-3)26(40-6)24(14-19)38-4/h7-15H,1-6H3,(H,30,33)
SMILES Code
COc1cc(NC(=O)N2C=C(N(C2=O)c3cc(OC)c(OC)c(OC)c3)c4ccc(Br)cc4)cc(OC)c1OC
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 614.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Fang L, Shen L, Fang Y, Hu Y, He Q, Yang B. MZ3 can induce G2/M-phase arrest and apoptosis in human leukemia cells. J Cancer Res Clin Oncol. 2008 Dec;134(12):1337-45. doi: 10.1007/s00432-008-0416-0. Epub 2008 May 20. PMID: 18491135. 2. Xu D, Fang L, Zhu Q, Hu Y, He Q, Yang B. Antimultidrug-resistant effect and mechanism of a novel CA-4 analogue MZ3 on leukemia cells. Pharmazie. 2008 Jul;63(7):528-33. PMID: 18717489.