MedKoo Cat#: 466046 | Name: A33903
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

A33903 is a 1,4-benzodiazepine analog that is being studied as a potential inhibitor of respiratory syncytial virus. This molecule was moderately active and demonstrated good pharmacokinetic properties.

Chemical Structure

A33903
A33903
CAS#70890-53-8

Theoretical Analysis

MedKoo Cat#: 466046

Name: A33903

CAS#: 70890-53-8

Chemical Formula: C17H15N3O2

Exact Mass: 293.1164

Molecular Weight: 293.33

Elemental Analysis: C, 69.61; H, 5.15; N, 14.33; O, 10.91

Price and Availability

Size Price Availability Quantity
5mg USD 150.00 Ready to Ship
10mg USD 250.00 Ready to Ship
25mg USD 550.00 Ready to Ship
50mg USD 950.00 Ready to Ship
100mg USD 1,650.00 Ready to Ship
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Related CAS #
No Data
Synonym
A33903; A 33903; A-33903;
IUPAC/Chemical Name
N-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)acetamide
InChi Key
MMXSDWJOQSEPSM-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H15N3O2/c1-11(21)18-16-17(22)19-14-10-6-5-9-13(14)15(20-16)12-7-3-2-4-8-12/h2-10,16H,1H3,(H,18,21)(H,19,22)
SMILES Code
CC(NC1C(NC2=CC=CC=C2C(C3=CC=CC=C3)=N1)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Biological target:
A33903 is a 1,4-benzodiazepine analog that is being studied as a potential inhibitor of respiratory syncytial virus.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 293.33 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Carter MC, Alber DG, Baxter RC, Bithell SK, Budworth J, Chubb A, Cockerill GS, Dowdell VC, Henderson EA, Keegan SJ, Kelsey RD, Lockyer MJ, Stables JN, Wilson LJ, Powell KL. 1,4-Benzodiazepines as inhibitors of respiratory syncytial virus. J Med Chem. 2006 Apr 6;49(7):2311-9. doi: 10.1021/jm051185t. PMID: 16570927.