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MedKoo Cat#: 466045 | Name: CARD-024

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CARD-024, also known as 1alpha-Hydroxyvitamin D5, is a vitamin D analog has been used in trials studying the treatment of Drug Safety and Heart; Disease, Activity.

Chemical Structure

CARD-024
CARD-024
CAS#187935-17-7

Theoretical Analysis

MedKoo Cat#: 466045

Name: CARD-024

CAS#: 187935-17-7

Chemical Formula: C29H48O2

Exact Mass: 428.3654

Molecular Weight: 428.70

Elemental Analysis: C, 81.25; H, 11.29; O, 7.46

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CARD-024; CARD024; CARD 024; 1alpha-Hydroxyvitamin D5; 1-Hydroxyvitamin D5; 1alpha-hydroxy-24-ethylcholecalciferol;
IUPAC/Chemical Name
9,10-Secostigmasta-5,7,10(19)-triene-1,3-diol, (1α,3β,5Z,7E)- (9CI) (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4R)-4-Ethyl-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-1,3-cyclohexanedio
InChi Key
NWFOBODUYTUMNC-QZBOTLMFSA-N
InChi Code
InChI=1S/C29H48O2/c1-7-22(19(2)3)11-10-20(4)26-14-15-27-23(9-8-16-29(26,27)6)12-13-24-17-25(30)18-28(31)21(24)5/h12-13,19-20,22,25-28,30-31H,5,7-11,14-18H2,1-4,6H3/b23-12+,24-13+/t20-,22-,25-,26-,27+,28+,29-/m1/s1
SMILES Code
CC[C@@H](C(C)C)CC[C@@H](C)[C@H]([C@]1(CCC/2)C)CC[C@@]1([H])C2=C\C=C3C[C@@H](O)C[C@H](O)C/3=C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 428.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Johnson LA, Sauder KL, Rodansky ES, Simpson RU, Higgins PD. CARD-024, a vitamin D analog, attenuates the pro-fibrotic response to substrate stiffness in colonic myofibroblasts. Exp Mol Pathol. 2012 Aug;93(1):91-8. doi: 10.1016/j.yexmp.2012.04.014. Epub 2012 Apr 18. PMID: 22542712; PMCID: PMC6443252.

View History

HM30181AK

HM30181AK