MedKoo Cat#: 577790 | Name: MS-377 free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MS-377 free base is a novel antipsychotic agent with selective affinity for sigma receptors

Chemical Structure

MS-377 free base
MS-377 free base
CAS#206862-30-8

Theoretical Analysis

MedKoo Cat#: 577790

Name: MS-377 free base

CAS#: 206862-30-8

Chemical Formula: C18H26ClN3O2

Exact Mass: 351.1714

Molecular Weight: 351.87

Elemental Analysis: C, 61.44; H, 7.45; Cl, 10.07; N, 11.94; O, 9.09

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MS-377 free base; MS 377 free base; MS377 free base
IUPAC/Chemical Name
(3R)-1-(4-Chlorophenyl)-3-((4-(2-methoxyethyl)-1-piperazinyl)methyl)-2-pyrrolidinone
InChi Key
DKVVPXLIRYCKCS-OAHLLOKOSA-N
InChi Code
1S/C18H26ClN3O2/c1-24-13-12-20-8-10-21(11-9-20)14-15-6-7-22(18(15)23)17-4-2-16(19)3-5-17/h2-5,15H,6-14H2,1H3/t15-/m1/s1
SMILES Code
COCCN1CCN(C[C@H]2CCN(C2=O)c3ccc(Cl)cc3)CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 351.87 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Takahashi S, Sonehara K, Takagi K, Miwa T, Horikomi K, Mita N, Nagase H, Iizuka K, Sakai K. Pharmacological profile of MS-377, a novel antipsychotic agent with selective affinity for sigma receptors. Psychopharmacology (Berl). 1999 Aug;145(3):295-302. doi: 10.1007/s002130051061. PMID: 10494578.