MR-1452 | CAS# 56649-73-1 | Biochemical

MedKoo Cat#: 577780 | Name: MR-1452

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MR-1452 is a kappa opiate receptor antagonist. FOR RESEARCH USE ONLY

Chemical Structure

MR-1452

CAS#56649-73-1

Theoretical Analysis

MedKoo Cat#: 577780

Name: MR-1452

CAS#: 56649-73-1

Chemical Formula: C19H23NO2

Exact Mass: 297.1729

Molecular Weight: 297.40

Elemental Analysis: C, 76.74; H, 7.80; N, 4.71; O, 10.76

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

MR-1452; MR 1452; MR1452

IUPAC/Chemical Name

2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-furylmethyl)-, (2R-(2-alpha,6-alpha,11R*))-

InChi Key

MSBGXQSDBDHIGV-MJXNMMHHSA-N

InChi Code

InChI=1S/C19H23NO2/c1-13-18-9-15-3-4-16(21)10-17(15)19(13,2)6-7-20(18)11-14-5-8-22-12-14/h3-5,8,10,12-13,18,21H,6-7,9,11H2,1-2H3/t13-,18+,19+/m0/s1

SMILES Code

C[C@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2Cc4cocc4

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 297.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Machuganska A, Kirov C, Somova L. The effect of naloxone and the kappa antagonist MR 1452 MS on myocardial infarction in rats. Methods Find Exp Clin Pharmacol. 1989 Sep;11(9):559-65. PMID: 2586202.