Synonym
PBI-4547; PBI4547; PBI 4547;
IUPAC/Chemical Name
sodium 2-(3,5-dipentylphenyl)acetate
InChi Key
OHGWIXASWPCFMS-UHFFFAOYSA-M
InChi Code
InChI=1S/C18H28O2.Na/c1-3-5-7-9-15-11-16(10-8-6-4-2)13-17(12-15)14-18(19)20;/h11-13H,3-10,14H2,1-2H3,(H,19,20);/q;+1/p-1
SMILES Code
[O-]C(CC1=CC(CCCCC)=CC(CCCCC)=C1)=O.[Na+]
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
298.40
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Chen LH, Zhang Q, Xie X, Nan FJ. Modulation of the G-Protein-Coupled Receptor 84 (GPR84) by Agonists and Antagonists. J Med Chem. 2020 Dec 24;63(24):15399-15409. doi: 10.1021/acs.jmedchem.0c01378. Epub 2020 Dec 2. PMID: 33267584.
2: Simard JC, Thibodeau JF, Leduc M, Tremblay M, Laverdure A, Sarra-Bournet F, Gagnon W, Ouboudinar J, Gervais L, Felton A, Letourneau S, Geerts L, Cloutier MP, Hince K, Corpuz R, Blais A, Quintela VM, Duceppe JS, Abbott SD, Blais A, Zacharie B, Laurin P, Laplante SR, Kennedy CRJ, Hébert RL, Leblond FA, Grouix B, Gagnon L. Fatty acid mimetic PBI-4547 restores metabolic homeostasis via GPR84 in mice with non-alcoholic fatty liver disease. Sci Rep. 2020 Jul 29;10(1):12778. doi: 10.1038/s41598-020-69675-8. PMID: 32728158; PMCID: PMC7391726.
