MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 465871 | Name: PF1070A

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PF1070A is a natural cyclic tetrapeptide HDAC Inhibitor through the inhibition of PfHDAC1 catalytic activity, potently inducing the synthesis of metallothionein.

Chemical Structure

PF1070A
PF1070A
CAS#146556-41-4

Theoretical Analysis

MedKoo Cat#: 465871

Name: PF1070A

CAS#: 146556-41-4

Chemical Formula: C31H44N4O6

Exact Mass: 568.3261

Molecular Weight: 568.72

Elemental Analysis: C, 65.47; H, 7.80; N, 9.85; O, 16.88

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
PF1070A; PF 1070A; PF-1070A;
IUPAC/Chemical Name
(3S,6R,9S,15aS)-6-benzyl-9-((S)-sec-butyl)-3-(6-((S)-oxiran-2-yl)-6-oxohexyl)octahydro-2H-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3H,12H)-tetraone
InChi Key
IEIMOAHNLVBBHL-IBCWPHNLSA-N
InChi Code
InChI=1S/C31H44N4O6/c1-3-20(2)27-31(40)35-17-11-10-15-24(35)30(39)32-22(14-8-5-9-16-25(36)26-19-41-26)28(37)33-23(29(38)34-27)18-21-12-6-4-7-13-21/h4,6-7,12-13,20,22-24,26-27H,3,5,8-11,14-19H2,1-2H3,(H,32,39)(H,33,37)(H,34,38)/t20-,22-,23+,24-,26-,27-/m0/s1
SMILES Code
O=C(N[C@H](C(N1[C@H](C(N[C@H]2CCCCCC([C@@H]3CO3)=O)=O)CCCC1)=O)[C@H](CC)C)[C@H](NC2=O)CC4=CC=CC=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 568.72 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Asahi I, Miura N, Yamabe Y, Toyoda H, Imura N, Koyama M, Naganuma A. PF1070A, a novel and potent inducer of the synthesis of metallothionein. Biochemistry. 1999 Aug 10;38(32):10415-23. doi: 10.1021/bi990655g. PMID: 10441136.