MedKoo Cat#: 471114 | Name: MS140
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

MS140 is a potent and selective CDK4/6 inhibitor.

Chemical Structure

MS140
MS140
CAS#2229974-83-6

Theoretical Analysis

MedKoo Cat#: 471114

Name: MS140

CAS#: 2229974-83-6

Chemical Formula: C39H40N10O7

Exact Mass: 760.3081

Molecular Weight: 760.81

Elemental Analysis: C, 61.57; H, 5.30; N, 18.41; O, 14.72

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
25mg USD 750.00 2 Weeks
50mg USD 1,250.00 2 Weeks
100mg USD 1,950.00 2 Weeks
200mg USD 2,950.00 2 Weeks
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Related CAS #
No Data
Synonym
MS140; MS 140; MS-140
IUPAC/Chemical Name
4-((2-(4-(6-((6-acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)-2-oxoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
InChi Key
IWFNIKIERKCKFZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C39H40N10O7/c1-21-26-19-42-39(45-34(26)48(23-6-3-4-7-23)37(55)32(21)22(2)50)43-29-12-10-24(18-41-29)46-14-16-47(17-15-46)31(52)20-40-27-9-5-8-25-33(27)38(56)49(36(25)54)28-11-13-30(51)44-35(28)53/h5,8-10,12,18-19,23,28,40H,3-4,6-7,11,13-17,20H2,1-2H3,(H,44,51,53)(H,41,42,43,45)
SMILES Code
O=C1CCC(N(C(C2=C3C=CC=C2NCC(N4CCN(C5=CC=C(NC6=NC=C(C(C)=C(C(C)=O)C(N7C8CCCC8)=O)C7=N6)N=C5)CC4)=O)=O)C3=O)C(N1)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 760.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Dong ZY, Narsing Rao MP, Wang HF, Fang BZ, Liu YH, Li L, Xiao M, Li WJ. Transcriptomic analysis of two endophytes involved in enhancing salt stress ability of Arabidopsis thaliana. Sci Total Environ. 2019 Oct 10;686:107-117. doi: 10.1016/j.scitotenv.2019.05.483. Epub 2019 Jun 1. PMID: 31176810.