MedKoo Cat#: 471113 | Name: IMT1B
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

IMT1B is a potent and specific allosteric inhibitor of mitochondrial RNA polymerase (POLRMT).

Chemical Structure

IMT1B
IMT1B
CAS#2304621-06-3

Theoretical Analysis

MedKoo Cat#: 471113

Name: IMT1B

CAS#: 2304621-06-3

Chemical Formula: C24H21ClFNO6

Exact Mass: 473.1040

Molecular Weight: 473.88

Elemental Analysis: C, 60.83; H, 4.47; Cl, 7.48; F, 4.01; N, 2.96; O, 20.26

Price and Availability

Size Price Availability Quantity
5mg USD 510.00 2 Weeks
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Related CAS #
No Data
Synonym
IMT1B, LDC203974; LDC 203974; LDC-203974
IUPAC/Chemical Name
(S)-1-((R)-2-((4-(2-chloro-4-fluorophenyl)-2-oxo-2H-chromen-7-yl)oxy)propanoyl)piperidine-3-carboxylic acid
InChi Key
PFEKWBKJUBCXDT-KGLIPLIRSA-N
InChi Code
InChI=1S/C24H21ClFNO6/c1-13(23(29)27-8-2-3-14(12-27)24(30)31)32-16-5-7-18-19(11-22(28)33-21(18)10-16)17-6-4-15(26)9-20(17)25/h4-7,9-11,13-14H,2-3,8,12H2,1H3,(H,30,31)/t13-,14+/m1/s1
SMILES Code
O=C([C@@H]1CN(C([C@H](OC2=CC(O3)=C(C=C2)C(C4=CC=C(F)C=C4Cl)=CC3=O)C)=O)CCC1)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 473.88 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL