MedKoo Cat#: 471106 | Name: PF-06733804
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

PF-06733804 is a potent inhibitor of tropomyosin-related kinase (Trk)

Chemical Structure

PF-06733804
PF-06733804
CAS# 1873373-33-1

Theoretical Analysis

MedKoo Cat#: 471106

Name: PF-06733804

CAS#: 1873373-33-1

Chemical Formula: C20H19F5N4O4

Exact Mass: 474.1330

Molecular Weight: 474.39

Elemental Analysis: C, 50.64; H, 4.04; F, 20.02; N, 11.81; O, 13.49

Price and Availability

Size Price Availability Quantity
5mg USD 450.00 2 Weeks
25mg USD 900.00 2 Weeks
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Related CAS #
No Data
Synonym
PF-06733804; PF06733804; PF 06733804
IUPAC/Chemical Name
(S)-6-amino-5-((4,4-difluoro-1-(2-(4-(trifluoromethoxy)phenyl)acetyl)pyrrolidin-3-yl)oxy)-N-methylnicotinamide
InChi Key
FTAFQADCGCSJAH-HNNXBMFYSA-N
InChi Code
InChI=1S/C20H19F5N4O4/c1-27-18(31)12-7-14(17(26)28-8-12)32-15-9-29(10-19(15,21)22)16(30)6-11-2-4-13(5-3-11)33-20(23,24)25/h2-5,7-8,15H,6,9-10H2,1H3,(H2,26,28)(H,27,31)/t15-/m0/s1
SMILES Code
NC1=C(O[C@H]2CN(C(CC3=CC=C(OC(F)(F)F)C=C3)=O)CC2(F)F)C=C(C(NC)=O)C=N1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 474.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL