Hoechst-33258 | CAS#unknown | DNA MGB

MedKoo Cat#: 465805 | Name: Hoechst-33258

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hoechst-33258 is a DNA minor groove binder (MGB).

Chemical Structure

Hoechst-33258

CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465805

Name: Hoechst-33258

CAS#: unknown

Chemical Formula: C25H24N6O

Exact Mass: 424.2012

Molecular Weight: 424.51

Elemental Analysis: C, 70.73; H, 5.70; N, 19.80; O, 3.77

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Hoechst-33258; Hoechst33258; Hoechst 33258;

IUPAC/Chemical Name

4-(5-(4-methylpiperazin-1-yl)-1H,3'H-[2,5'-bibenzo[d]imidazol]-2'-yl)phenol

InChi Key

INAAIJLSXJJHOZ-UHFFFAOYSA-N

InChi Code

InChI=1S/C25H24N6O/c1-30-10-12-31(13-11-30)18-5-9-21-23(15-18)29-25(27-21)17-4-8-20-22(14-17)28-24(26-20)16-2-6-19(32)7-3-16/h2-9,14-15,32H,10-13H2,1H3,(H,26,28)(H,27,29)

SMILES Code

CN(CC1)CCN1C2=CC3=C(NC(C4=CC=C(N=C(C5=CC=C(O)C=C5)N6)C6=C4)=N3)C=C2

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 424.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Ronchi A, Bellorini M, Mongelli N, Mantovani R. CCAAT-box binding protein NF-Y (CBF, CP1) recognizes the minor groove and distorts DNA. Nucleic Acids Res. 1995 Nov 25;23(22):4565-72. doi: 10.1093/nar/23.22.4565. PMID: 8524643; PMCID: PMC307426.