PF-06726304 acetate is a potent and SAM-competitive EZH2 (Enhancer of Zeste Homolog 2) lysine methyltransferase inhibitor. PF-06726304 displayed robust in vivo antitumor growth activity and dose-dependent de-repression of EZH2 target genes.
MedKoo Cat#: 471103
Name: PF-06726304 acetate
CAS#: 2080306-28-9
Chemical Formula: C24H25Cl2N3O5
Exact Mass: 505.1170
Molecular Weight: 506.38
Elemental Analysis: C, 56.93; H, 4.98; Cl, 14.00; N, 8.30; O, 15.80
The following data is based on the product molecular weight 506.38 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
