DB-60 is a novel macrocyclic immunoproteasome inhibitor, effectively inhibiting the catalytic activity of immunoproteasome (iP) in ABCB1-overexpressing cells (IC50: 105 nM) and having metabolic stability superior to its linear counterpart.
MedKoo Cat#: 465767
Name: DB-60
CAS#: unknown
Chemical Formula: C34H43N3O6
Exact Mass: 589.3152
Molecular Weight: 589.73
Elemental Analysis: C, 69.25; H, 7.35; N, 7.13; O, 16.28
The following data is based on the product molecular weight 589.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
