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MedKoo Cat#: 465741 | Name: DX3-234

Description:

WARNING: This product is for research use only, not for human or veterinary use.

DX3-234 is a potent Oxidative Phosphorylation Inhibitor. DX3-234 is a close analogue of DX3-235.

Chemical Structure

DX3-234
DX3-234
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465741

Name: DX3-234

CAS#: unknown

Chemical Formula: C25H35N5O6S2

Exact Mass: 565.2029

Molecular Weight: 565.70

Elemental Analysis: C, 53.08; H, 6.24; N, 12.38; O, 16.97; S, 11.33

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
DX3-234; DX3234; DX3 234;
IUPAC/Chemical Name
(R)-(1-((4-(cyclobutylsulfonyl)phenyl)sulfonyl)piperidin-3-yl)(4-(3-isopropyl-1,2,4-oxadiazol-5-yl)piperazin-1-yl)methanone
InChi Key
GZNMPLSGMXGEJY-LJQANCHMSA-N
InChi Code
InChI=1S/C25H35N5O6S2/c1-18(2)23-26-25(36-27-23)29-15-13-28(14-16-29)24(31)19-5-4-12-30(17-19)38(34,35)22-10-8-21(9-11-22)37(32,33)20-6-3-7-20/h8-11,18-20H,3-7,12-17H2,1-2H3/t19-/m1/s1
SMILES Code
O=C([C@H]1CN(S(=O)(C2=CC=C(S(=O)(C3CCC3)=O)C=C2)=O)CCC1)N4CCN(C5=NC(C(C)C)=NO5)CC4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 565.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Xue D, Xu Y, Kyani A, Roy J, Dai L, Sun D, Neamati N. Discovery and Lead Optimization of Benzene-1,4-disulfonamides as Oxidative Phosphorylation Inhibitors. J Med Chem. 2022 Jan 4. doi: 10.1021/acs.jmedchem.1c01509. Epub ahead of print. PMID: 34982568.