VD2173 is a potent Inhibitor (IC50= 2.2 nM) of HGF-Activating Serine Proteases Overcome Resistance to Receptor Tyrosine Kinase Inhibitors and Block Lung Cancer Progression. VD2173 potently inhibits matriptase and hepsin, which was tested in parallel alongside the acyclic inhibitor ZFH7116 using both in vitro and in vivo models of lung cancer.
MedKoo Cat#: 465723
Name: VD2173
CAS#: unknown
Chemical Formula: C31H45N9O6S
Exact Mass: 671.3214
Molecular Weight: 671.82
Elemental Analysis: C, 55.42; H, 6.75; N, 18.76; O, 14.29; S, 4.77
The following data is based on the product molecular weight 671.82 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
