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MedKoo Cat#: 465719 | Name: SLEC-11

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SLEC-11 is a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer.

Chemical Structure

SLEC-11
SLEC-11
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465719

Name: SLEC-11

CAS#: unknown

Chemical Formula: C18H17FN2O

Exact Mass: 296.1325

Molecular Weight: 296.35

Elemental Analysis: C, 72.95; H, 5.78; F, 6.41; N, 9.45; O, 5.40

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
SLEC-11; SLEC11; SLEC 11;
IUPAC/Chemical Name
N-(4-fluorobenzyl)-6-methoxy-2-methylquinolin-4-amine
InChi Key
NWJCMSSQJWHTAI-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H17FN2O/c1-12-9-18(20-11-13-3-5-14(19)6-4-13)16-10-15(22-2)7-8-17(16)21-12/h3-10H,11H2,1-2H3,(H,20,21)
SMILES Code
COC1=CC=C(N=C(C)C=C2NCC3=CC=C(F)C=C3)C2=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 296.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Luxenburger A, Bougen-Zhukov N, Fraser MG, Beetham H, Harris LD, Schmidt D, Cameron SA, Guilford PJ, Evans GB. Discovery of AL-GDa62 as a Potential Synthetic Lethal Lead for the Treatment of Gastric Cancer. J Med Chem. 2021 Dec 23;64(24):18114-18142. doi: 10.1021/acs.jmedchem.1c01609. Epub 2021 Dec 8. PMID: 34878770.