MedKoo Cat#: 465673 | Name: MMV006429

Description:

WARNING: This product is for research use only, not for human or veterinary use.

MMV006429 is a potential PfATP4 inhibitor.

Chemical Structure

MMV006429
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465673

Name: MMV006429

CAS#: unknown

Chemical Formula: C22H23N3O3S

Exact Mass: 409.1460

Molecular Weight: 409.50

Elemental Analysis: C, 64.53; H, 5.66; N, 10.26; O, 11.72; S, 7.83

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
MMV006429; MMV 006429; MMV-006429;
IUPAC/Chemical Name
2-isobutyl-N-(5-methylisoxazol-3-yl)-1-oxo-3-(thiophen-2-yl)-1,2,3,4-tetrahydroisoquinoline-4-carboxamide
InChi Key
YCGDUUJJIKNHJN-UHFFFAOYSA-N
InChi Code
InChI=1S/C22H23N3O3S/c1-13(2)12-25-20(17-9-6-10-29-17)19(15-7-4-5-8-16(15)22(25)27)21(26)23-18-11-14(3)28-24-18/h4-11,13,19-20H,12H2,1-3H3,(H,23,24,26)
SMILES Code
O=C1N(CC(C)C)C(C2=CC=CS2)C(C(NC3=NOC(C)=C3)=O)C4=C1C=CC=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 409.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Santos BM, Dias BKM, Nakabashi M, Garcia CRS. The Knockout for G Protein- Coupled Receptor-Like PfSR25 Increases the Susceptibility of Malaria Parasites to the Antimalarials Lumefantrine and Piperaquine but Not to Medicine for Malaria Venture Compounds. Front Microbiol. 2021 Mar 15;12:638869. doi: 10.3389/fmicb.2021.638869. PMID: 33790879; PMCID: PMC8006397. 2: Malebo HM, D'Alessandro S, Ebstie YA, Sorè H, Tenoh Guedoung AR, Katani SJ, Parapini S, Taramelli D, Habluetzel A. In vitro Multistage Malaria Transmission Blocking Activity of Selected Malaria Box Compounds. Drug Des Devel Ther. 2020 Apr 28;14:1593-1607. doi: 10.2147/DDDT.S242883. PMID: 32425505; PMCID: PMC7196193.