Sezolamide | CAS# 123291-07-6 | Biochemical

MedKoo Cat#: 577513 | Name: Sezolamide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sezolamide is a carbonic anhydrase inhibitor.

Chemical Structure

Sezolamide

CAS#123291-07-6

Theoretical Analysis

MedKoo Cat#: 577513

Name: Sezolamide

CAS#: 123291-07-6

Chemical Formula: C11H18N2O4S3

Exact Mass: 338.0429

Molecular Weight: 338.46

Elemental Analysis: C, 39.04; H, 5.36; N, 8.28; O, 18.91; S, 28.42

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

MK 927; MK927; MK-927; Sezolamide

IUPAC/Chemical Name

4-(isobutylamino)-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide

InChi Key

JFLUCCKXAYBETQ-UHFFFAOYSA-N

InChi Code

InChI=1S/C11H18N2O4S3/c1-7(2)6-13-9-3-4-19(14,15)11-8(9)5-10(18-11)20(12,16)17/h5,7,9,13H,3-4,6H2,1-2H3,(H2,12,16,17)

SMILES Code

CC(C)CNC1CCS(=O)(=O)c2sc(cc12)S(=O)(=O)N

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 338.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Gunning FP, Greve EL, Bron AM, Bosc JM, Royer JG, George JL, Lesure P, Sirbat D. Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: a multiple-dose efficacy study. Graefes Arch Clin Exp Ophthalmol. 1993 Jul;231(7):384-8. doi: 10.1007/BF00919645. PMID: 8406063. 2. Lippa EA, Schuman JS, Higginbotham EJ, Kass MA, Weinreb RN, Skuta GL, Epstein DL, Shaw B, Holder DJ, Deasy DA, et al. MK-507 versus sezolamide. Comparative efficacy of two topically active carbonic anhydrase inhibitors. Ophthalmology. 1991 Mar;98(3):308-12; discussion 312-3. doi: 10.1016/s0161-6420(91)32295-4. PMID: 2023750.