Verlukast | CAS# 115104-28-4 | Biochemical

MedKoo Cat#: 577496 | Name: Verlukast

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Verlukast is a LTD4 receptor antagonist.

Chemical Structure

Verlukast

CAS#115104-28-4

Theoretical Analysis

MedKoo Cat#: 577496

Name: Verlukast

CAS#: 115104-28-4

Chemical Formula: C26H27ClN2O3S2

Exact Mass: 514.1152

Molecular Weight: 515.08

Elemental Analysis: C, 60.63; H, 5.28; Cl, 6.88; N, 5.44; O, 9.32; S, 12.45

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

L 660,711; L 660711; L660711; L-660711; MK 0571; MK0571; MK-0571; MK 571; MK571; MK-571; Verlukast

IUPAC/Chemical Name

Propanoic acid, 3-(((3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)((3-(dimethylamino)-3-oxopropyl)thio)methyl)thio)-, (E)-

InChi Key

AXUZQJFHDNNPFG-UXBLZVDNSA-N

InChi Code

InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+

SMILES Code

CN(C)C(=O)CCSC(SCCC(=O)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

To be determined

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 515.08 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1. Jones TR, Zamboni R, Belley M, Champion E, Charette L, Ford-Hutchinson AW, Gauthier JY, Leger S, Lord A, Masson P, et al. Pharmacology of the leukotriene antagonist verlukast: the (R)-enantiomer of MK-571. Can J Physiol Pharmacol. 1991 Dec;69(12):1847-54. doi: 10.1139/y91-273. PMID: 1666333. 2. Lammers JW, Van Daele P, Van den Elshout FM, Decramer M, Buntinx A, De Lepeleire I, Friedman B. Bronchodilator properties of an inhaled leukotriene D4 antagonist (verlukast--MK-0679) in asthmatic patients. Pulm Pharmacol. 1992 Jun;5(2):121-5. doi: 10.1016/0952-0600(92)90029-g. PMID: 1611229.