C3 DEPTOR Inhibitor is a Icaritin Derivative, and a Novel Putative DEPTOR Inhibitors for Multiple Myeloma Treatment. Compound C3 exhibited better antimultiple myeloma activity with an IC50 of 1.09 μM for RPMI 8226 cells, induced RPMI 8226 apoptosis, and blocked the cell cycle in the S phase.
MedKoo Cat#: 465614
Name: C3 DEPTOR Inhibitor
CAS#: 2615911-12-9
Chemical Formula: C24H16Cl2FNO4
Exact Mass: 471.0440
Molecular Weight: 472.29
Elemental Analysis: C, 61.03; H, 3.41; Cl, 15.01; F, 4.02; N, 2.97; O, 13.55
The following data is based on the product molecular weight 472.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
