MedKoo Cat#: 471059 | Name: Terevalefim

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Terevalefim, an hepatocyte growth factor (HGF) mimetic, selectively activates the c-Met receptor.

Chemical Structure

Terevalefim
Terevalefim
CAS#1070881-42-3

Theoretical Analysis

MedKoo Cat#: 471059

Name: Terevalefim

CAS#: 1070881-42-3

Chemical Formula: C9H8N2S

Exact Mass: 176.0400

Molecular Weight: 176.24

Elemental Analysis: C, 61.34; H, 4.58; N, 15.90; S, 18.19

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Terevalefim; Refanalin; ANG-3777; ANG3777; ANG 3777;SNV-003; SNV003; SNV 003
IUPAC/Chemical Name
(E)-3-(2-(thiophen-2-yl)vinyl)-1H-pyrazole
InChi Key
FOHWAQGURRYJFK-ONEGZZNKSA-N
InChi Code
InChI=1S/C9H8N2S/c1-2-9(12-7-1)4-3-8-5-6-10-11-8/h1-7H,(H,10,11)/b4-3+
SMILES Code
C1(/C=C/C2=CC=CS2)=NNC=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 176.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Bromberg JS, Weir MR, Gaber AO, Yamin MA, Goldberg ID, Mayne TJ, Cal W, Cooper M. Transplantation. 2021 Feb 1;105(2):443-450. 2. Ayad S, Neylan JF, Mayne TJ, Gouveia D, Swaminathan M. Kidney Int Rep. 2020 Sep 25;5(12):2325-2332. 3.Vincenti F, Kim J, Gouveia D, Pelle G, Mayne TJ, Neylan JF. Kidney Int Rep. 2020 Nov 13;6(2):296-303