LUN-15112 is used to probe RNA structure and conformation in live cells, using the cross-linking of matched RNAs and deep sequencing or COMRADES method. LUN-15112 crosslinks the RNA and the azide enables subsequent click reaction with biotin. The COMRADES method has been used to determine the architecture of the Zika virus RNA genome inside cells, and identified multiple site-specific interactions with human noncoding RNAs. It has also been used to map RNA-RNA interactions along the SARS-CoV-2 genome and subgenomes inside cells. LUN-15112 is cell permeable. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).
MedKoo Cat#: 465596
Name: LUN-15112
CAS#: 1352815-11-2
Chemical Formula: C23H30N4O6
Exact Mass: 458.2165
Molecular Weight: 458.52
Elemental Analysis: C, 60.25; H, 6.60; N, 12.22; O, 20.94
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 45.9 | 100.00 | |
| Ethanol | 22.9 | 50.00 |
The following data is based on the product molecular weight 458.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
