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MedKoo Cat#: 577456 | Name: Mivazerol hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mivazerol hydrochloride is an alpha 2-adrenoceptor agonist.

Chemical Structure

Mivazerol hydrochloride
Mivazerol hydrochloride
CAS#127170-73-4

Theoretical Analysis

MedKoo Cat#: 577456

Name: Mivazerol hydrochloride

CAS#: 127170-73-4

Chemical Formula: C11H12ClN3O2

Exact Mass: 253.0618

Molecular Weight: 253.69

Elemental Analysis: C, 52.08; H, 4.77; Cl, 13.97; N, 16.56; O, 12.61

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Mivazerol hydrochloride; Mivazerol HCl
IUPAC/Chemical Name
Benzamide, 2-hydroxy-3-(1H-imidazol-4-ylmethyl)-, monohydrochloride
InChi Key
YJJUPMPFHKRGKP-UHFFFAOYSA-N
InChi Code
InChI=1S/C11H11N3O2.ClH/c12-11(16)9-3-1-2-7(10(9)15)4-8-5-13-6-14-8;/h1-3,5-6,15H,4H2,(H2,12,16)(H,13,14);1H
SMILES Code
Cl.NC(=O)c1cccc(Cc2c[nH]cn2)c1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 253.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Oliver MF, Goldman L, Julian DG, Holme I. Effect of mivazerol on perioperative cardiac complications during non-cardiac surgery in patients with coronary heart disease: the European Mivazerol Trial (EMIT). Anesthesiology. 1999 Oct;91(4):951-61. PubMed PMID: 10519497. 2: Kimura T, Sato K, Nishikawa T, Tobe Y, Masaki Y. Effect of mivazerol, a alpha-agonist, on striatal norepinephrine concentration during transient forebrain ischemia in rats. Acta Anaesthesiol Scand. 2008 Aug;52(7):997-1002. doi: 10.1111/j.1399-6576.2008.01683.x. Epub 2008 May 20. PubMed PMID: 18494845. 3: Zhang X, Kindel GH, Wülfert E, Hanin I. Effects of immobilization stress on hippocampal monoamine release: modification by mivazerol, a new alpha 2-adrenoceptor agonist. Neuropharmacology. 1995 Dec;34(12):1661-72. PubMed PMID: 8788964. 4: Roekaerts PM, Prinzen FW, Willigers HM, De Lange S. The effects of alpha 2-adrenergic stimulation with mivazerol on myocardial blood flow and function during coronary artery stenosis in anesthetized dogs. Anesth Analg. 1996 Apr;82(4):702-11. PubMed PMID: 8615484. 5: Richer C, Gobert J, Noyer M, Wülfert E, Giudicelli JF. Peripheral alpha 2-adrenoceptor-mediated sympathoinhibitory effects of mivazerol. Fundam Clin Pharmacol. 1996;10(6):529-37. PubMed PMID: 8985723.