MedKoo Cat#: 465565 | Name: RUN-00530
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

RUN-00530 is a functionalized cereblon ligand for PROTAC® research and development. It incorporates an E3 ligase ligand with a terminal piperidine for onward chemistry to generate Protein Degraders with rigid linkers. It is part of a range of functionalized tool molecules for PROTAC® Degrader R&D. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).

Chemical Structure

RUN-00530
RUN-00530
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465565

Name: RUN-00530

CAS#: unknown

Chemical Formula: C23H30Cl2FN5O4

Exact Mass: 529.1659

Molecular Weight: 530.42

Elemental Analysis: C, 52.08; H, 5.70; Cl, 13.37; F, 3.58; N, 13.20; O, 12.07

Price and Availability

Size Price Availability Quantity
25mg USD 550.00 2 Weeks
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Related CAS #
No Data
Synonym
RUN-00530; RUN00530; RUN 00530; Pomalidomide 5'-fluoro-6'-piperazine-4-methylpiperidine;
IUPAC/Chemical Name
2-(2,6-dioxopiperidin-3-yl)-5-fluoro-6-(4-(piperidin-4-ylmethyl)piperazin-1-yl)isoindoline-1,3-dione dihydrochloride
InChi Key
RPBQFDUBJGNGHE-UHFFFAOYSA-N
InChi Code
InChI=1S/C23H28FN5O4.2ClH/c24-17-11-15-16(23(33)29(22(15)32)18-1-2-20(30)26-21(18)31)12-19(17)28-9-7-27(8-10-28)13-14-3-5-25-6-4-14;;/h11-12,14,18,25H,1-10,13H2,(H,26,30,31);2*1H
SMILES Code
FC1=C(C=C2C(N(C3CCC(NC3=O)=O)C(C2=C1)=O)=O)N4CCN(CC5CCNCC5)CC4.Cl.Cl
Appearance
Solid powder
Purity
>95% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 530.42 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL