MedKoo Cat#: 465563 | Name: GUN29829
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GUN29829 is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand with a terminal piperazine for onward chemistry to generate Protein Degraders with rigid linkers. It is Part of a range of functionalized tool molecules for PROTAC® Degrader R&D. This product has no formal name. For the convenience of scientific communication, we named it by combining its InChi Key (3 letters from the first letter of each section) with the last 5 digit of its CAS#) according to MedKoo Chemical Nomenclature (https://www.medkoo.com/page/naming).

Chemical Structure

GUN29829
GUN29829
CAS#2228029-82-9

Theoretical Analysis

MedKoo Cat#: 465563

Name: GUN29829

CAS#: 2228029-82-9

Chemical Formula: C17H19ClN4O4

Exact Mass: 378.1095

Molecular Weight: 378.81

Elemental Analysis: C, 53.90; H, 5.06; Cl, 9.36; N, 14.79; O, 16.89

Price and Availability

Size Price Availability Quantity
100mg USD 450.00 2 Weeks
250mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
GUN29829; GUN 29829; GUN-29829; Pomalidomide 5'-piperazine HCl; Thalidomide-piperazine HCl; Thalidomide-piperazine hydrochloride
IUPAC/Chemical Name
2-(2,6-dioxopiperidin-3-yl)-5-(piperazin-1-yl)isoindoline-1,3-dione hydrochloride
InChi Key
GZNLORFTQXVXFE-UHFFFAOYSA-N
InChi Code
InChI=1S/C17H18N4O4.ClH/c22-14-4-3-13(15(23)19-14)21-16(24)11-2-1-10(9-12(11)17(21)25)20-7-5-18-6-8-20;/h1-2,9,13,18H,3-8H2,(H,19,22,23);1H
SMILES Code
O=C1N(C2CCC(NC2=O)=O)C(C3=CC(N4CCNCC4)=CC=C13)=O.Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 378.81 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL