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MedKoo Cat#: 465560 | Name: VC701

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VC701 is a novel ligand of translocator protein (TSPO) receptors.

Chemical Structure

VC701
VC701
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465560

Name: VC701

CAS#: unknown

Chemical Formula: C25H21FN2O

Exact Mass: 384.1638

Molecular Weight: 384.45

Elemental Analysis: C, 78.10; H, 5.51; F, 4.94; N, 7.29; O, 4.16

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
Bulk Inquiry
Related CAS #
No Data
Synonym
VC701; VC 701; VC-701;
IUPAC/Chemical Name
N-benzyl-3-(fluoromethyl)-N-methyl-4-phenylquinoline-2-carboxamide
InChi Key
BIFFCCPIXSXSCB-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H21FN2O/c1-28(17-18-10-4-2-5-11-18)25(29)24-21(16-26)23(19-12-6-3-7-13-19)20-14-8-9-15-22(20)27-24/h2-15H,16-17H2,1H3
SMILES Code
O=C(C1=NC2=CC=CC=C2C(C3=CC=CC=C3)=C1CF)N(CC4=CC=CC=C4)C
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 384.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Valtorta S, Lo Dico A, Raccagni I, Martelli C, Pieri V, Rainone P, Todde S, Zinnhardt B, De Bernardi E, Coliva A, Politi LS, Viel T, Jacobs AH, Galli R, Ottobrini L, Vaira V, Moresco RM. Imaging Metformin Efficacy as Add-On Therapy in Cells and Mouse Models of Human EGFR Glioblastoma. Front Oncol. 2021 May 3;11:664149. doi: 10.3389/fonc.2021.664149. PMID: 34012924; PMCID: PMC8126706. 2: Murtaj V, Belloli S, Di Grigoli G, Pannese M, Ballarini E, Rodriguez-Menendez V, Marmiroli P, Cappelli A, Masiello V, Monterisi C, Bellelli G, Panina- Bordignon P, Moresco RM. Age and Sex Influence the Neuro-inflammatory Response to a Peripheral Acute LPS Challenge. Front Aging Neurosci. 2019 Nov 5;11:299. doi: 10.3389/fnagi.2019.00299. PMID: 31749696; PMCID: PMC6848890. 3: Belloli S, Zanotti L, Murtaj V, Mazzon C, Di Grigoli G, Monterisi C, Masiello V, Iaccarino L, Cappelli A, Poliani PL, Politi LS, Moresco RM. 18F-VC701-PET and MRI in the in vivo neuroinflammation assessment of a mouse model of multiple sclerosis. J Neuroinflammation. 2018 Feb 5;15(1):33. doi: 10.1186/s12974-017-1044-x. PMID: 29402285; PMCID: PMC5800080. 4: Di Grigoli G, Monterisi C, Belloli S, Masiello V, Politi LS, Valenti S, Paolino M, Anzini M, Matarrese M, Cappelli A, Moresco RM. Radiosynthesis and Preliminary Biological Evaluation of [18F]VC701, a Radioligand for Translocator Protein. Mol Imaging. 2015;14. doi: 10.2310/7290.2015.00007. PMID: 26044669.