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MedKoo Cat#: 577409 | Name: Mildiomycin

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Mildiomycin is a nucleoside antibiotic that inhibits protein synthesis.

Chemical Structure

Mildiomycin
Mildiomycin
CAS#67527-71-3

Theoretical Analysis

MedKoo Cat#: 577409

Name: Mildiomycin

CAS#: 67527-71-3

Chemical Formula: C19H30N8O9

Exact Mass: 514.2136

Molecular Weight: 514.50

Elemental Analysis: C, 44.36; H, 5.88; N, 21.78; O, 27.99

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Antibiotic B-98891; B-98891; B98891; B 98891; Mildiomycin
IUPAC/Chemical Name
2-((2S,3S,6R)-3-((S)-2-amino-3-hydroxypropanamido)-6-(4-amino-5-(hydroxymethyl)-2-oxopyrimidin-1(2H)-yl)-3,6-dihydro-2H-pyran-2-yl)-5-((diaminomethylene)amino)-2,4-dihydroxypentanoic acid
InChi Key
QKJJCZYFXJCKRX-HZHKWBLPSA-N
InChi Code
InChI=1S/C19H30N8O9/c20-10(7-29)15(31)25-11-1-2-12(27-5-8(6-28)14(21)26-18(27)34)36-13(11)19(35,16(32)33)3-9(30)4-24-17(22)23/h1-2,5,9-13,28-30,35H,3-4,6-7,20H2,(H,25,31)(H,32,33)(H2,21,26,34)(H4,22,23,24)/t9?,10-,11-,12+,13-,19?/m0/s1
SMILES Code
N[C@@H](CO)C(=O)N[C@H]1C=C[C@@H](O[C@@H]1C(O)(CC(O)CN=C(N)N)C(=O)O)N2C=C(CO)C(=NC2=O)N
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Toxicity Data: Mouse, LD50, Intraperitoneal (1020mg/kg) | Effects: Somnolence, Altered Sleep Time (including change in righting reflex)

Preparing Stock Solutions

The following data is based on the product molecular weight 514.50 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1. Feduchi E, Cosín M, Carrasco L. Mildiomycin: a nucleoside antibiotic that inhibits protein synthesis. J Antibiot (Tokyo). 1985 Mar;38(3):415-9. doi: 10.7164/antibiotics.38.415. PMID: 2409064. 2. Harada S, Kishi T. Isolation and characterization of mildiomycin, a new nucleoside antibiotic. J Antibiot (Tokyo). 1978 Jun;31(6):519-24. doi: 10.7164/antibiotics.31.519. PMID: 681233.

View History

Biotin-PEG12-NHS ester

Biotin-PEG12-NHS ester

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