MedKoo Cat#: 414912 | Name: Phetharbital

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Phetharbital is a barbiturate derivative. It has anticonvulsant effects and relatively weak sedative action, and is considered to have a low abuse potential.

Chemical Structure

Phetharbital
Phetharbital
CAS#357-67-5

Theoretical Analysis

MedKoo Cat#: 414912

Name: Phetharbital

CAS#: 357-67-5

Chemical Formula: C14H16N2O3

Exact Mass: 260.1161

Molecular Weight: 260.29

Elemental Analysis: C, 64.60; H, 6.20; N, 10.76; O, 18.44

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Phetharbital; NSC 85043; NSC85043; NSC-85043
IUPAC/Chemical Name
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-diethyl-1-phenyl- (9CI)
InChi Key
ILORKHQGIMGDFN-UHFFFAOYSA-N
InChi Code
InChI=1S/C14H16N2O3/c1-3-14(4-2)11(17)15-13(19)16(12(14)18)10-8-6-5-7-9-10/h5-9H,3-4H2,1-2H3,(H,15,17,19)
SMILES Code
O=C1NC(C(CC)(CC)C(N1C2=CC=CC=C2)=O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 260.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hunter J, Thompson RP, Rake MO, Williams R. Controlled trial of phetharbital, a non-hypnotic barbiturate, in unconugated hyperbilirubinaemia. Br Med J. 1971 May 29;2(5760):497-9. doi: 10.1136/bmj.2.5760.497. PMID: 4931488; PMCID: PMC1795997. 2: Southren AL, Gordon GG, Tochimoto S, Krikun E, Krieger D, Jacobson M, Kuntzman R. Effect of N-phenylbarbital (phetharbital) on the metabolism of testosterone and cortisol in man. J Clin Endocrinol Metab. 1969 Feb;29(2):251-6. doi: 10.1210/jcem-29-2-251. PMID: 4884888. 3: Kuntzman R, Jacobson M, Levin W, Conney AH. Stimulatory effect of N-phenylbarbital (phetharbital) on cortisol hydroxylation in man. Biochem Pharmacol. 1968 Apr;17(4):565-71. doi: 10.1016/0006-2952(68)90272-4. PMID: 5649552. 4: Adachi Y, Yamamoto T. Influence of drugs and chemicals upon hepatic enzymes and proteins. II. The effects of various barbiturates on the induction and reduction of hepatic cytoplasmic organic anion-binding proteins. Gastroenterol Jpn. 1976;11(1):23-30. doi: 10.1007/BF02775447. PMID: 10220.