MedKoo Cat#: 465448 | Name: VUF15259

Description:

WARNING: This product is for research use only, not for human or veterinary use.

VUF15259 is a novel inhibitor of Hbp secretion, activating σE stress, impairing Hbp secretion and decreasing the abundance of OMPs, consistent with impaired BAM function.

Chemical Structure

VUF15259
VUF15259
CAS#unknown

Theoretical Analysis

MedKoo Cat#: 465448

Name: VUF15259

CAS#: unknown

Chemical Formula: C13H19Cl3N2O

Exact Mass: 324.0563

Molecular Weight: 325.66

Elemental Analysis: C, 47.95; H, 5.88; Cl, 32.66; N, 8.60; O, 4.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
VUF15259; VUF 15259; VUF-15259;
IUPAC/Chemical Name
2-(4-aminopiperidin-1-yl)-1-(3,4-dichlorophenyl)ethan-1-ol hydrochloride
InChi Key
MGPZARPVFDYALF-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H18Cl2N2O.ClH/c14-11-2-1-9(7-12(11)15)13(18)8-17-5-3-10(16)4-6-17;/h1-2,7,10,13,18H,3-6,8,16H2;1H
SMILES Code
OC(C1=CC=C(Cl)C(Cl)=C1)CN2CCC(N)CC2.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 325.66 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Steenhuis M, Abdallah AM, de Munnik SM, Kuhne S, Sterk GJ, van den Berg van Saparoea B, Westerhausen S, Wagner S, van der Wel NN, Wijtmans M, van Ulsen P, Jong WSP, Luirink J. Inhibition of autotransporter biogenesis by small molecules. Mol Microbiol. 2019 Jul;112(1):81-98. doi: 10.1111/mmi.14255. Epub 2019 May 3. PMID: 30983025; PMCID: PMC6850105.