OAN00639 is a novel Potent PD-L1 Inhibitor (IC50 1.8 nM), binding to human PD-L1 (hPD-L1) with a KD value of 3.34 nM, without showing any binding to hPD-1, blocking PD-1/PD-L1 interaction with an EC50 value of 375 nM.
MedKoo Cat#: 465432
Name: OAN00639
CAS#: unknown
Chemical Formula: C30H25BrClN3O6
Exact Mass: 637.0615
Molecular Weight: 638.90
Elemental Analysis: C, 56.40; H, 3.94; Br, 12.51; Cl, 5.55; N, 6.58; O, 15.02
The following data is based on the product molecular weight 638.90 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
