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MedKoo Cat#: 577309 | Name: Chloropromazine methoiodide

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Chloropromazine methoiodide is the salt form of chlorpromazine, a phenothiazine and traditional antipsychotic agent with anti-emetic activity.

Chemical Structure

Chloropromazine methoiodide
Chloropromazine methoiodide
CAS#362-02-7

Theoretical Analysis

MedKoo Cat#: 577309

Name: Chloropromazine methoiodide

CAS#: 362-02-7

Chemical Formula: C18H22ClIN2S

Exact Mass: 460.0237

Molecular Weight: 460.80

Elemental Analysis: C, 46.92; H, 4.81; Cl, 7.69; I, 27.54; N, 6.08; S, 6.96

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Chloropromazine methoiodide; Methochlorpromazine iodide
IUPAC/Chemical Name
Ammonium, (3-(2-chlorophenothiazin-10-yl)propyl)trimethyl-, iodide
InChi Key
SHVVOGYMOKHKHG-UHFFFAOYSA-M
InChi Code
InChI=1S/C18H22ClN2S.HI/c1-21(2,3)12-6-11-20-15-7-4-5-8-17(15)22-18-10-9-14(19)13-16(18)20;/h4-5,7-10,13H,6,11-12H2,1-3H3;1H/q+1;/p-1
SMILES Code
[I-].C[N+](C)(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
To be determined
Shelf Life
>2 years if stored properly
Drug Formulation
To be determined
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 460.80 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Halayqa M, Domańska U. PLGA biodegradable nanoparticles containing perphenazine or chlorpromazine hydrochloride: effect of formulation and release. Int J Mol Sci. 2014 Dec 22;15(12):23909-23. doi: 10.3390/ijms151223909. PubMed PMID: 25535080; PubMed Central PMCID: PMC4284797. 2: Nagaraja P, Aradhana N, Suma A, Shivakumar A, Chamaraja NA. Quantification of antioxidants by using chlorpromazine hydrochloride: application of the method to food and medicinal plant samples. Anal Sci. 2014;30(2):251-6. PubMed PMID: 24521912. 3: Liu JM, Lin LP, Wang XX, Lin X, Zhou P, Lin SQ, Zheng ZY. Highly sensitive detection of residual chlorpromazine hydrochloride with solid substrate room temperature phosphorimetry. J Fluoresc. 2012 Jul;22(4):1087-94. doi: 10.1007/s10895-012-1047-z. Epub 2012 Apr 24. PubMed PMID: 22527301. 4: Rai V, Dayan N, Michniak-Kohn B. A comparative evaluation of photo-toxic effect of fractionated melanin and chlorpromazine hydrochloride on human (dermal fibroblasts and epidermal keratinocytes) and mouse cell line/s (fibroblast Balb/c 3T3). Toxicol In Vitro. 2011 Mar;25(2):538-44. doi: 10.1016/j.tiv.2010.11.017. Epub 2010 Dec 4. PubMed PMID: 21134440.